Minicells as a Damage Disposal Mechanism in Escherichia coli
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چکیده
منابع مشابه
Toxic waste disposal in Escherichia coli.
About 10% of the nalidixic acid-resistant (Nal(r)) mutants in a transposition-induced library exhibited a growth factor requirement as the result of cysH, icdA, metE, or purB mutation. Resistance in all of these mutants required a functional AcrAB-TolC efflux pump, but the EmrAB-TolC pump played no obvious role. Transcription of acrAB was increased in each type of Nal(r) mutant. In the icdA and...
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Nitrofurazone is reduced by cellular nitroreductases to form N(2)-deoxyguanine (N(2)-dG) adducts that are associated with mutagenesis and lethality. Much attention recently has been given to the role that the highly conserved polymerase IV (Pol IV) family of polymerases plays in tolerating adducts induced by nitrofurazone and other N(2)-dG-generating agents, yet little is known about how nitrof...
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متن کاملDeoxyribonucleic Acid Damage in Escherichia coli
INTRODUCTION............................................................ 61 PROCESSING OF DAMAGED DNA ............................................................ 61 SOS REGULATORY NETWORK ............................................................. 61 Present Model for SOS Regulation ............................................................ 62 SOS Responses ...................................
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ژورنال
عنوان ژورنال: mSphere
سال: 2018
ISSN: 2379-5042
DOI: 10.1128/msphere.00428-18